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临床转化神经科学  2015, Vol. 1 Issue (2): 86-91    DOI: 10.18679/CN11-6030/R.2015.010
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Morphological predictors of posterior communicating artery aneurysms rupture
Nan Lv, Yibin Fang, Ying Yu, Jinyu Xu, Jianmin Liu, Qinghai Huang
Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
Morphological predictors of posterior communicating artery aneurysms rupture
Nan Lv, Yibin Fang, Ying Yu, Jinyu Xu, Jianmin Liu, Qinghai Huang
Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
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摘要 Objective: The conflicting findings of previous morphological studies on intracranial aneurysm rupture may be caused by the different locations of aneurysms. We aimed to determine the independent risk factors of aneurysm rupture by focusing on only posterior communicating artery (PcomA) aneurysms. Methods: In 89 PcomA aneurysms (58 ruptured, 31 unruptured), clinical and morphological characteristics were compared between the ruptured and unruptured groups. Multivariate logistic regression analysis was performed to determine the independent predictors for the rupture status of PcomA aneurysms. Results: In univariate analyses, the aneurysm dome size, aspect ratio, size ratio, dome-to-neck ratio, and inflow angle were significant parameters. With multivariate analyses, only the aneurysm dome size and inflow angle were significantly associated with the rupture status of PcomA aneurysms. Conclusions: Morphology was related with rupture of PcomA aneurysms. The aneurysm dome size and inflow angle were found to be the independent parameters characterizing the rupture status of PcomA aneurysms.
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Nan Lv
Yibin Fang
Ying Yu
Jinyu Xu
Jianmin Liu
Qinghai Huang
关键词:  intracranial aneurysm  posterior communicating artery  rupture  morphology    
Abstract: Objective: The conflicting findings of previous morphological studies on intracranial aneurysm rupture may be caused by the different locations of aneurysms. We aimed to determine the independent risk factors of aneurysm rupture by focusing on only posterior communicating artery (PcomA) aneurysms. Methods: In 89 PcomA aneurysms (58 ruptured, 31 unruptured), clinical and morphological characteristics were compared between the ruptured and unruptured groups. Multivariate logistic regression analysis was performed to determine the independent predictors for the rupture status of PcomA aneurysms. Results: In univariate analyses, the aneurysm dome size, aspect ratio, size ratio, dome-to-neck ratio, and inflow angle were significant parameters. With multivariate analyses, only the aneurysm dome size and inflow angle were significantly associated with the rupture status of PcomA aneurysms. Conclusions: Morphology was related with rupture of PcomA aneurysms. The aneurysm dome size and inflow angle were found to be the independent parameters characterizing the rupture status of PcomA aneurysms.
Key words:  intracranial aneurysm    posterior communicating artery    rupture    morphology
收稿日期:  2015-08-03      修回日期:  2015-09-18           出版日期:  2015-12-15      发布日期:  2015-12-15      期的出版日期:  2015-12-15
通讯作者:  Qinghai Huang, E-mail:ocinhqh@163.com    E-mail:  ocinhqh@163.com
引用本文:    
Nan Lv, Yibin Fang, Ying Yu, Jinyu Xu, Jianmin Liu, Qinghai Huang. Morphological predictors of posterior communicating artery aneurysms rupture[J]. 临床转化神经科学, 2015, 1(2): 86-91.
Nan Lv, Yibin Fang, Ying Yu, Jinyu Xu, Jianmin Liu, Qinghai Huang. Morphological predictors of posterior communicating artery aneurysms rupture. Translational Neuroscience and Clinics, 2015, 1(2): 86-91.
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http://tnc.tsinghuajournals.com/CN/10.18679/CN11-6030/R.2015.010  或          http://tnc.tsinghuajournals.com/CN/Y2015/V1/I2/86
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