Posterior mediastinal ganglioneuroma:A case report and literature review
Linkai Jing1,2, Zhenxing Sun2, Yi Guo2, Youtu Wu2, James Wang2, Guihuai Wang2
1 School of Clinical Medicine, Tsinghua University, Beijing 100084, China;
2 Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China
Posterior mediastinal ganglioneuroma:A case report and literature review
Linkai Jing1,2, Zhenxing Sun2, Yi Guo2, Youtu Wu2, James Wang2, Guihuai Wang2
1 School of Clinical Medicine, Tsinghua University, Beijing 100084, China;
2 Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China
摘要 Objectives: Ganglioneuroma is a rare,benign neurogenic tumor arising from the sympathetic ganglia.In this report,we reviewed and summarized the clinical features, treatment,and prognosis of a posterior mediastinal ganglioneuroma. Case:Here,we report on a 29-year-old man referred to us with transient pain in the right side of the chest,lasting for three days.Physical examination revealed no abnormalities. The results of routine laboratory tests were within the normal ranges.Thoracic spinal magnetic resonance imaging showed a well-defined,solid mass in the right paravertebral region at the T5-T8 level,measuring 7.5 cm×4.2 cm×1.5 cm.To accurately locate the lesion during surgery,O-arm intraoperative imaging was used in conjunction with the Stealth Station navigation system.The tumor was completely excised and no related complications occurred.The tumor was an encapsulated mass with a solid,homogenous,grayish-tan cut surface.Histopathological examinations confirmed that the mass was a ganglioneuroma. Conclusions:Ganglioneuroma is a rare,benign tumor.Prior to treatment,a careful imaging evaluation is necessary in order to obtain an accurate diagnosis.A definitive diagnosis can be made by histological examination.En bloc resection is the preferred treatment for ganglioneuroma as it has an excellent prognosis.
Abstract: Objectives: Ganglioneuroma is a rare,benign neurogenic tumor arising from the sympathetic ganglia.In this report,we reviewed and summarized the clinical features, treatment,and prognosis of a posterior mediastinal ganglioneuroma. Case:Here,we report on a 29-year-old man referred to us with transient pain in the right side of the chest,lasting for three days.Physical examination revealed no abnormalities. The results of routine laboratory tests were within the normal ranges.Thoracic spinal magnetic resonance imaging showed a well-defined,solid mass in the right paravertebral region at the T5-T8 level,measuring 7.5 cm×4.2 cm×1.5 cm.To accurately locate the lesion during surgery,O-arm intraoperative imaging was used in conjunction with the Stealth Station navigation system.The tumor was completely excised and no related complications occurred.The tumor was an encapsulated mass with a solid,homogenous,grayish-tan cut surface.Histopathological examinations confirmed that the mass was a ganglioneuroma. Conclusions:Ganglioneuroma is a rare,benign tumor.Prior to treatment,a careful imaging evaluation is necessary in order to obtain an accurate diagnosis.A definitive diagnosis can be made by histological examination.En bloc resection is the preferred treatment for ganglioneuroma as it has an excellent prognosis.
Linkai Jing, Zhenxing Sun, Yi Guo, Youtu Wu, James Wang, Guihuai Wang. Posterior mediastinal ganglioneuroma:A case report and literature review[J]. 临床转化神经科学, 2017, 3(3): 147-150.
Linkai Jing, Zhenxing Sun, Yi Guo, Youtu Wu, James Wang, Guihuai Wang. Posterior mediastinal ganglioneuroma:A case report and literature review. Translational Neuroscience and Clinics, 2017, 3(3): 147-150.
20171023160950 Figure 1 A 29-year-old male presented with transient chest pain lasting for three days. Magnetic resonance images before surgery (a, b, c) showed a solid, well-defined mass measuring 7.5 cm × 4.2 cm × 1.5 cm, in the right paravertebral region at the T5-T8 level. Histopathological examination (d) confirmed the final diagnosis of ganglioneuroma. No radiological signs of recurrence were observed seventeen months after the surgery (e).
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